Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the therapy of numerous myeloma. Its synthesis or study is crucial for making sure the purity and basic safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound during the synthesis of imatinib, a drug that targets unique sorts of most cancers, which include Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their study is crucial for optimizing the manufacturing course of action and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to take care of breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast cancer. Several intermediates assist in the (7a synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers which include ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, which have various programs, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style two diabetes that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous 7-dihydro-4-oxo-1H-pymol[2 Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of assorted gluconic acid derivatives, which are used in meals, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication utilized to manage kind 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).